It is binding of drug to plasma protein in blood component. Binding of drugs to plasma proteins is reversible. Various plasma protein to which drug binds includes Albumin, α1-Acid glycoprotein (orosomucoid), lipoprotein, globulins, etc. Proteins are large molecules that form the structural part of most organs and make up enzymes and hormones that regulate body functions. Digoxin is a drug used to treat heart failure and abnormal heart rhythms. Digoxin levels must be monitored because the drug has a narrow safety range. Digoxin dosage may be adjusted based on levels measured. VALIDATE® ready-to-use kits are designed to assist in the documentation of linearity, calibration verification and verification of linear range required by many inspection agencies. Digoxin, sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is taken by mouth or by injection into a vein. Available online at Metabolism Clinical and Experimental 58 (2009) 55 – 61 Acute effects of digoxin on plasma aldosterone and. DigiFab® 40 mg/vial Digoxin Immune Fab PL 21744/0001 Powder for Solution for Infusion Protherics UK Ltd 1 DigiFab®, 40mg/vial digoxin immune Fab, powder for solution for infusion DIGITEK® (digoxin) Tablets, USP. DESCRIPTION. DIGITEK (digoxin) is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium. DIGIBIND® Digoxin Immune Fab (Ovine) DESCRIPTION. DIGIBIND, Digoxin Immune Fab (Ovine), is a sterile lyophilized powder of antigen binding fragments (Fab) derived from specific antidigoxin antibodies raised in sheep. These may arise from effects on the renal excretion, tissue binding, plasma protein binding, distribution within the body, gut absorptive capacity and sensitivity to digoxin.